SCHEMBL3700810

SCHEMBL3700810

CCC=CCC=CCC=CCC=CCC=CCCOC(C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
MAPT P10636 4/20 0.50
CYP19A1 P11511 4/20 0.50
PPARG P37231 3/20 0.50
OXER1 Q8TDS5 3/20 0.50
RXRA P19793 2/20 0.50
FFAR1 O14842 2/20 0.50
PTGS1 P23219 4/20 0.47
F7 P08709 3/20 0.47
F3 P13726 3/20 0.47
PPARA Q07869 3/20 0.47
KMT2A Q03164 2/20 0.47
PPARD Q03181 2/20 0.47
ADORA3 P0DMS8 2/20 0.47
NR1I2 O75469 2/20 0.45
PTGS2 P35354 2/20 0.45
CYP3A4 P08684 2/20 0.45
ALOX15 P16050 2/20 0.45
HSD17B10 Q99714 2/20 0.45
TDP1 Q9NUW8 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3700806 1.00 ALDH1A1 (0.50) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL3705382 1.00 ALDH1A1 (0.50) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL3705379 1.00 ALDH1A1 (0.50) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL289575 0.90 ALDH1A1 (0.53) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL289576 0.90 ALDH1A1 (0.53) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL2784802 0.89 ALDH1A1 (0.53) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL2784807 0.89 ALDH1A1 (0.53) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL2784608 0.87 ALDH1A1 (0.55) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL2784610 0.87 ALDH1A1 (0.55) ALDH1A1MAPTCYP19A1PPARGOXER1
SCHEMBL18944613 0.85 ALDH1A1 (0.54) ALDH1A1MAPTCYP19A1PPARGOXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140221439-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS PRONOVA BIOPHARMA NORGE AS (NO) 2014-08-07 US disclosed
US-8735436-B2 Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas PRONOVA BIOPHARMA NORGE AS (NO) 2014-05-27 US disclosed
US-20120122940-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS PRONOVA BIOPHARMA NORGE AS (NO) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122940-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS FFAR2, FFAR3, FFAR1 ALDH1A1 695/4885MAPT 4175/4885CYP19A1 1476/4885
US-20140221439-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS FFAR2, FFAR3, FFAR1 ALDH1A1 663/4885MAPT 4130/4885CYP19A1 1451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.