Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3808572 | 0.91 | HTR2C (0.41) | HTR2CSLC6A4HTR2ANAMPTABCC9 | |
| SCHEMBL3699812 | 0.89 | HTR2C (0.38) | HTR2CSLC6A4HTR2AABCC9ABCC8 | |
| SCHEMBL3698341 | 0.89 | HTR2C (0.38) | HTR2CSLC6A4HTR2ANAMPTF2 | |
| SCHEMBL4126102 | 0.88 | NAMPT (0.37) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3695801 | 0.88 | HTR2C (0.38) | HTR2CSLC6A4HTR2ANAMPTABCC9 | |
| SCHEMBL3693157 | 0.88 | HTR2C (0.43) | HTR2CSLC6A4HTR2ANAMPTABCC9 | |
| SCHEMBL3700225 | 0.86 | HTR2C (0.39) | HTR2CSLC6A4HTR2AF2 | |
| SCHEMBL3703100 | 0.85 | HTR2C (0.36) | HTR2CSLC6A4HTR2ANAMPTABCC9 | |
| Hydrochloric Acid SCHEMBL3707035 | 0.85 | HTR2C (0.37) | HTR2CSLC6A4HTR2ANAMPTABCC9 | |
| SCHEMBL4566347 | 0.85 | HTR2C (0.39) | HTR2CSLC6A4HTR2AABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |