Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706675 | 0.92 | HTR2C (0.39) | HTR2CSLC6A4HTR2A | |
| SCHEMBL3695801 | 0.92 | HTR2C (0.38) | HTR2CSLC6A4HTR2AABCC9ABCC8 | |
| SCHEMBL3688570 | 0.90 | HTR2C (0.38) | HTR2CSLC6A4HTR2AKAT8GPBAR1 | |
| SCHEMBL3705293 | 0.89 | HTR2C (0.39) | HTR2CSLC6A4HTR2AABCC9ABCC8 | |
| SCHEMBL3699812 | 0.89 | HTR2C (0.38) | HTR2CSLC6A4HTR2AABCC9ABCC8 | |
| SCHEMBL3808572 | 0.89 | HTR2C (0.41) | HTR2CSLC6A4HTR2AABCC9ABCC8 | |
| SCHEMBL4123658 | 0.88 | TAS2R14 (0.35) | KAT8GPBAR1KAT5PTGER2HTT | |
| SCHEMBL3693157 | 0.85 | HTR2C (0.43) | HTR2CSLC6A4HTR2AABCC9ABCC8 | |
| SCHEMBL3701316 | 0.85 | HTR2C (0.38) | HTR2CSLC6A4HTR2AABCC9ABCC8 | |
| SCHEMBL3703100 | 0.85 | HTR2C (0.36) | HTR2CSLC6A4HTR2AABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |