Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363911 | 0.87 | GPBAR1 (0.52) | FFAR1MMP2MMP12GPBAR1DHFR | |
| SCHEMBL370198 | 0.79 | WNT3A (0.40) | FFAR1GPBAR1GABRPGABRDGABRA1 | |
| SCHEMBL1390427 | 0.79 | GPBAR1 (0.41) | GPBAR1KMT2A | |
| SCHEMBL1390129 | 0.78 | GPBAR1 (0.49) | FFAR1GPBAR1GABRPGABRDGABRA1 | |
| SCHEMBL370012 | 0.77 | GPBAR1 (0.57) | FFAR1GPBAR1 | |
| SCHEMBL362814 | 0.77 | GPBAR1 (0.67) | FFAR1GPBAR1DHFRFFAR4 | |
| SCHEMBL362813 | 0.77 | GPBAR1 (0.67) | FFAR1GPBAR1DHFRFFAR4 | |
| SCHEMBL10241023 | 0.77 | GPBAR1 (0.67) | FFAR1GPBAR1DHFRFFAR4 | |
| SCHEMBL369800 | 0.76 | GPBAR1 (0.54) | FFAR1MMP2MMP12GPBAR1 | |
| SCHEMBL1390267 | 0.75 | GPBAR1 (0.48) | GPBAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |