Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512155 | 0.87 | BCAT2 (0.55) | MYCBCAT2KEAP1NFE2L2IKBKB | |
| SCHEMBL3824312 | 0.86 | MYC (0.66) | MYCALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL1788703 | 0.85 | BCAT2 (0.59) | MYCBCAT2KEAP1NFE2L2IKBKB | |
| SCHEMBL3135445 | 0.84 | MYC (0.53) | MYCBCAT2KEAP1NFE2L2IKBKB | |
| SCHEMBL5742619 | 0.84 | MYC (0.53) | MYCBCAT2KEAP1NFE2L2IKBKB | |
| SCHEMBL158431 | 0.83 | CD44 (0.48) | MYCBCAT2ALDH1A1HPGDLMNA | |
| SCHEMBL29442190 | 0.83 | CD44 (0.48) | MYCBCAT2ALDH1A1HPGDLMNA | |
| SCHEMBL28471957 | 0.81 | MYC (0.59) | MYCBCAT2KEAP1NFE2L2IKBKB | |
| SCHEMBL3804575 | 0.81 | ALDH1A1 (0.50) | BCAT2KEAP1NFE2L2IKBKBALDH1A1 | |
| SCHEMBL4138458 | 0.79 | MYC (0.72) | MYCBCAT2KEAP1NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197835-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | Prosidion Limited (GB) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009030962-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | PROSIDION LIMITED (GB) | 2009-03-12 | — | — | WO | disclosed |