Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671318 | 0.88 | PDE4A (0.44) | BCAT2IKBKBMEN1KMT2APDE4A | |
| SCHEMBL3135452 | 0.84 | BCAT2 (0.47) | BCAT2MEN1KMT2AGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL29287793 | 0.83 | CA1 (0.47) | BCAT2MEN1KMT2AGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL29287828 | 0.83 | CA1 (0.47) | BCAT2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL17829925 | 0.77 | BCAT2 (0.56) | BCAT2IKBKBMEN1KMT2AALDH1A1 | |
| SCHEMBL1250167 | 0.77 | BCAT2 (0.55) | BCAT2IKBKBMEN1KMT2AGAA | |
| SCHEMBL31255442 | 0.76 | BCAT2 (0.42) | BCAT2IKBKBMEN1KMT2AGAA | |
| SCHEMBL27824725 | 0.76 | CHEK2 (0.50) | BCAT2IKBKBMEN1KMT2AGAA | |
| SCHEMBL3698514 | 0.75 | FABP4 (0.40) | BCAT2IKBKBMEN1KMT2AGAA | |
| SCHEMBL141445 | 0.75 | HSD17B10 (0.50) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197835-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | Prosidion Limited (GB) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009030962-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | PROSIDION LIMITED (GB) | 2009-03-12 | — | — | WO | disclosed |