Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178750 | 0.89 | MEN1 (0.44) | HDAC1MEN1KMT2APTGES | |
| SCHEMBL1194034 | 0.83 | MEN1 (0.53) | HDAC1MEN1KMT2A | |
| SCHEMBL3705301 | 0.79 | HDAC1 (0.43) | HDAC1MEN1KMT2A | |
| SCHEMBL1178083 | 0.76 | PTGES (0.47) | HDAC1MEN1KMT2APTGS2PTGES | |
| SCHEMBL1178620 | 0.74 | PTGS2 (0.50) | PTGS2PTGES | |
| SCHEMBL1177945 | 0.73 | MEN1 (0.42) | HDAC1MEN1KMT2APTGES | |
| SCHEMBL1179533 | 0.72 | PTGS2 (0.42) | PTGS2PTGES | |
| SCHEMBL1178855 | 0.70 | PTGS2 (0.37) | PTGS2PTGES | |
| SCHEMBL1178046 | 0.70 | PTGES (0.64) | PTGS2PTGES | |
| SCHEMBL1178475 | 0.69 | MEN1 (0.56) | HDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |