Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 3/20 | 0.63 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.63 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648389 | 0.77 | ABCC9 (1.00) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL2129487 | 0.77 | ABCC9 (1.00) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL2129489 | 0.77 | ABCC9 (1.00) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL8747789 | 0.75 | KMT2A (0.63) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL1610107 | 0.72 | MEN1 (0.51) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL6647586 | 0.69 | ABCC9 (0.62) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL2497201 | 0.69 | ABCC9 (0.62) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL11168464 | 0.68 | ABCC9 (0.60) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL11153475 | 0.67 | LMNA (0.45) | ABCC9KCNJ11KMT2AMEN1CYP1A2 | |
| SCHEMBL11162954 | 0.67 | ABCC9 (0.80) | ABCC9KCNJ11KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111518-A1 | TREATMENT AND PREVENTION OF WHITE MATTER INJURY WITH KATP CHANNEL ACTIVATORS | YALE UNIVERSITY (US) | 2010-09-30 | — | — | WO | claimed |