SCHEMBL3701775

SCHEMBL3701775

CCN(CC)c1ccc(N=Nc2ccc(N=Nc3ccc(N=Nc4ccc(N(CC)CC)cc4C)cc3)cc2)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.51
MAPT P10636 11/20 0.49
RAB9A P51151 9/20 0.49
TDP1 Q9NUW8 8/20 0.49
KMT2A Q03164 7/20 0.49
NPC1 O15118 7/20 0.49
MEN1 O00255 6/20 0.49
LMNA P02545 4/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPK1 P28482 5/20 0.47
L3MBTL1 Q9Y468 5/20 0.47
POLB P06746 1/20 0.47
MMP14 P50281 1/20 0.47
ALDH1A1 P00352 10/20 0.45
ATM Q13315 2/20 0.45
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
PSMD14 O00487 2/20 0.41
MITF O75030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3437420 0.94 S100B (0.46) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL16016940 0.92 RAB9A (0.46) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL24849962 0.90 S100B (0.43) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL12509970 0.90 S100B (0.43) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL12069761 0.88 MAPT (0.47) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL16016848 0.87 RAB9A (0.44) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL7530765 0.87 S100B (0.41) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL3437423 0.87 CYP3A4 (0.44) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL23236821 0.86 RAB9A (0.47) S100BMAPTRAB9ATDP1KMT2A
SCHEMBL7534641 0.85 CYP3A4 (0.42) S100BMAPTRAB9ATDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754295-B2 Single substrate guest-host polymer dispersed liquid crystal displays INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-07-13 US claimed
WO-2008005202-A2 SINGLE SUBSTRATE GUEST-HOST POLYMER LIQUID CRYSTAL DISPLAYS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-01-10 WO claimed
US-20080003379-A1 electronically modulated imaging layer comprises a dichroic or pleochroic dye in a fixed latex polymer matrix; low cost; display having excellent brightness, high contrast, and low switching voltage EASTMAN KODAK COMPANY 2008-01-03 US claimed
US-7754295-B2 Single substrate guest-host polymer dispersed liquid crystal displays INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-07-13 US disclosed
WO-2008005202-A2 SINGLE SUBSTRATE GUEST-HOST POLYMER LIQUID CRYSTAL DISPLAYS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-01-10 WO disclosed
US-20080003379-A1 electronically modulated imaging layer comprises a dichroic or pleochroic dye in a fixed latex polymer matrix; low cost; display having excellent brightness, high contrast, and low switching voltage EASTMAN KODAK COMPANY 2008-01-03 US disclosed
US-4308161-A FOR UPGRADING BLACK COLOR OF BLACK LIQUID CRYSTAL DISPLAYS GENERAL ELECTRIC COMPANY (US) 1981-12-29 US disclosed
US-4228030-A Liquid crystal compositions GENERAL ELECTRIC COMPANY (US) 1980-10-14 US disclosed
US-4179395-A LIQUID CRYSTALS FOR USE IN DISPLAYS GENERAL ELECTRIC COMPANY (US) 1979-12-18 US disclosed
US-4128497-A TRISAZO DYE GENERAL ELECTRIC COMPANY (US) 1978-12-05 US disclosed