Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.56 |
| ▸ | CLK2 | P49760 | 3/20 | 0.56 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | CLK3 | P49761 | 1/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.56 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.51 |
| ▸ | CDK2 | P24941 | 6/20 | 0.48 |
| ▸ | PRKACA | P17612 | 5/20 | 0.48 |
| ▸ | CDC7 | O00311 | 4/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3698007 | 0.99 | GSK3B (0.54) | GSK3BDYRK1ACLK4CDK5CLK2 | |
| SCHEMBL3698927 | 0.81 | NPC1 (0.54) | CALM1CAMKK2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13604781 | 0.80 | EGFR (0.50) | GSK3BDYRK1ACLK4CDK5CLK2 | |
| SCHEMBL3698061 | 0.80 | CALM1 (0.47) | ROCK2ROCK1PRKACACALM1CAMKK2 | |
| Hydrochloric Acid SCHEMBL3701265 | 0.79 | CALM1 (0.46) | ROCK2ROCK1PRKACACALM1CAMKK2 | |
| SCHEMBL3707288 | 0.77 | CALM1 (0.47) | ROCK2CALM1CAMKK2SLC6A2SLC6A4 | |
| Acetic Acid SCHEMBL3704776 | 0.77 | FDPS (0.48) | GSK3BDYRK1ACLK4CDK5CLK2 | |
| SCHEMBL3702044 | 0.77 | CALM1 (0.49) | DYRK1ACALM1CAMKK2 | |
| Hydrochloric Acid SCHEMBL3695870 | 0.76 | CALM1 (0.46) | ROCK2CALM1CAMKK2SLC6A2SLC6A4 | |
| SCHEMBL27713721 | 0.76 | CALM1 (0.51) | CALM1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851199-B1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | AVENTIS PHARMA INC (US) | 2012-05-16 | — | — | EP | claimed |
| EP-1851199-B1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | AVENTIS PHARMA INC (US) | 2012-05-16 | — | — | EP | disclosed |
| US-7625889-B2 | Substituted bis aryl and heteroaryl compounds as selective 5HT2A antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-7625889-B2 | Substituted bis aryl and heteroaryl compounds as selective 5HT2A antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20070265309-A1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070265309-A1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265309-A1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | HTR2A, HTR2B, HTR2C | GSK3B 1534/4885DYRK1A 773/4885CLK4 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.