Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 13/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 12/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3696895 | 0.89 | SLC16A3 (0.44) | SLC16A3SLC16A1 | |
| SCHEMBL3700362 | 0.87 | SLC16A3 (0.38) | SLC16A3SLC16A1TRPM8FPR1PDE4B | |
| SCHEMBL3696613 | 0.85 | SLC16A3 (0.37) | SLC16A3SLC16A1TRPM8FPR1PDE4B | |
| SCHEMBL3701987 | 0.85 | SLC16A3 (0.36) | SLC16A3SLC16A1PDE4B | |
| SCHEMBL3696908 | 0.84 | ALDH1A1 (0.39) | SLC16A3SLC16A1FPR1 | |
| SCHEMBL3701584 | 0.83 | SLC16A3 (0.39) | SLC16A3SLC16A1PDE4B | |
| SCHEMBL3698141 | 0.83 | SLC16A3 (0.37) | SLC16A3SLC16A1TRPM8FPR1PDE4B | |
| SCHEMBL3698156 | 0.82 | KMT2A (0.38) | SLC16A3SLC16A1 | |
| SCHEMBL3702179 | 0.82 | HTR2C (0.43) | SLC16A3SLC16A1 | |
| SCHEMBL3691770 | 0.82 | SLC16A3 (0.40) | SLC16A3SLC16A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |