Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370233 | 1.00 | NPC1 (0.42) | NPC1ADAM17AOC3CPA1MEN1 | |
| SCHEMBL10065821 | 1.00 | NPC1 (0.42) | NPC1ADAM17AOC3CPA1MEN1 | |
| SCHEMBL370232 | 1.00 | NPC1 (0.42) | NPC1ADAM17AOC3CPA1MEN1 | |
| SCHEMBL809500 | 0.79 | NPC1 (0.40) | NPC1ADAM17AOC3CPA1MEN1 | |
| SCHEMBL809527 | 0.79 | NPC1 (0.40) | NPC1ADAM17AOC3CPA1MEN1 | |
| SCHEMBL812559 | 0.79 | NPC1 (0.40) | NPC1ADAM17AOC3CPA1MEN1 | |
| SCHEMBL14930795 | 0.78 | LMNA (0.52) | AOC3ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL12056716 | 0.78 | NPC1 (0.44) | NPC1ADAM17CPA1MEN1KMT2A | |
| SCHEMBL1984016 | 0.77 | NPC1 (0.46) | NPC1ADAM17AOC3CPA1MEN1 | |
| SCHEMBL1987865 | 0.76 | TAAR1 (0.52) | NPC1ADAM17CPA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | claimed |
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | disclosed |