Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873376 | 0.85 | LMNA (0.58) | LMNAHKDC1AOC3SLC6A2SLC6A3 | |
| SCHEMBL10064961 | 0.85 | SLC6A2 (0.56) | LMNAHKDC1AOC3SLC6A2SLC6A3 | |
| SCHEMBL28973920 | 0.84 | LMNA (0.52) | LMNAHKDC1AOC3SLC6A2SLC6A3 | |
| SCHEMBL23050196 | 0.82 | LMNA (0.54) | LMNAHKDC1AOC3SLC6A2SLC6A3 | |
| SCHEMBL9843786 | 0.81 | HKDC1 (0.55) | LMNAHKDC1AOC3SLC6A2SLC6A3 | |
| SCHEMBL24990899 | 0.79 | AOC3 (0.61) | LMNAAOC3SLC6A2SLC6A3CHRM2 | |
| SCHEMBL18759601 | 0.79 | LMNA (0.56) | LMNAAOC3SLC6A2SLC6A4KDM4E | |
| SCHEMBL8157573 | 0.78 | AOC3 (0.48) | LMNAHKDC1AOC3SLC6A2SLC6A3 | |
| SCHEMBL370232 | 0.78 | NPC1 (0.42) | LMNAAOC3CYP3A4MAPTTDP1 | |
| SCHEMBL370231 | 0.78 | NPC1 (0.42) | LMNAAOC3CYP3A4MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116445-A1 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116445-A1 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | TIMCC, CYCS, CTRC | LMNA 2114/4885HKDC1 3363/4885AOC3 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.