Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063741 | 0.83 | EPHX1 (0.41) | HSD11B1CTSKMEN1KMT2A | |
| SCHEMBL3063742 | 0.83 | EPHX1 (0.41) | HSD11B1CTSKMEN1KMT2A | |
| SCHEMBL6964671 | 0.73 | RAB9A (0.44) | HSD11B1JAK1JAK2RAB9AKIT | |
| SCHEMBL1693841 | 0.72 | RAB9A (0.43) | HSD11B1JAK1JAK2RAB9AKIT | |
| SCHEMBL3717661 | 0.72 | RAB9A (0.43) | HSD11B1JAK1JAK2RAB9AKIT | |
| SCHEMBL4595765 | 0.72 | DPP4 (0.48) | HSD11B1JAK1JAK2RAB9AKIT | |
| SCHEMBL5967869 | 0.71 | RAB9A (0.43) | HSD11B1JAK1JAK2RAB9AGAA | |
| SCHEMBL32684148 | 0.70 | MEN1 (0.47) | HSD11B1CTSKGAAMEN1KMT2A | |
| SCHEMBL1693309 | 0.70 | RAB9A (0.43) | HSD11B1JAK1JAK2RAB9AGAA | |
| SCHEMBL24131326 | 0.69 | RAB9A (0.48) | HSD11B1JAK1JAK2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091411-A1 | PIPERIDINYL CYCLIC AMIDO ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2010-08-12 | — | — | WO | disclosed |