Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533477 | 0.81 | PIK3CD (0.39) | DRD3KCNH2MEN1KMT2ADRD2 | |
| SCHEMBL12384747 | 0.81 | TSHR (0.42) | KCNH2MEN1KMT2A | |
| SCHEMBL19981954 | 0.75 | TRPV3 (0.31) | KCNH2 | |
| SCHEMBL1570116 | 0.75 | GSK3B (0.32) | — | |
| SCHEMBL1570119 | 0.73 | KCNA3 (0.39) | MEN1KMT2A | |
| SCHEMBL1693823 | 0.73 | GNAI3 (0.39) | — | |
| SCHEMBL1286703 | 0.73 | TSHR (0.45) | MEN1KMT2A | |
| SCHEMBL5184024 | 0.73 | SMN1; SMN2 (0.42) | DRD3KCNH2MEN1KMT2ADRD2 | |
| SCHEMBL5184021 | 0.73 | SMN1; SMN2 (0.42) | DRD3KCNH2MEN1KMT2ADRD2 | |
| SCHEMBL18663999 | 0.73 | MEN1 (0.30) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081904-A1 | 4 ( 1H) -PYRIDINONE DERIVATIVES AND THEIR USE AS ANTIMALARIA AGENTS | GLAXO GROUP LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |