Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436307 | 0.87 | AKR1C3 (0.57) | GAASMN1; SMN2GPR119TSHRLMNA | |
| SCHEMBL13698470 | 0.86 | SMN1; SMN2 (0.74) | GAAALOX12SMN1; SMN2KDM4ELMNA | |
| SCHEMBL2959519 | 0.85 | GPR119 (0.74) | GPR119KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL30185679 | 0.82 | CKS1B (0.56) | GAASMN1; SMN2GPR119TSHRLMNA | |
| SCHEMBL5235727 | 0.82 | CKS1B (0.56) | GAASMN1; SMN2GPR119TSHRLMNA | |
| SCHEMBL28517145 | 0.79 | GAA (0.49) | GAAALOX12SMN1; SMN2GPR119KDM4E | |
| SCHEMBL21876050 | 0.78 | GPR119 (0.55) | GAAALOX12SMN1; SMN2GPR119OPRM1 | |
| SCHEMBL8352974 | 0.78 | GPR119 (0.59) | GPR119LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL21876731 | 0.78 | GPR119 (0.59) | GPR119LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL8355282 | 0.78 | GPR119 (0.53) | GAAALOX12SMN1; SMN2GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |