Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.55 |
| ▸ | CDC7 | O00311 | 8/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705312 | 0.89 | XDH (0.70) | XDHCDC7DBF4ABCC4ABCB11 | |
| SCHEMBL3703604 | 0.87 | CDC7 (0.52) | XDHCDC7DBF4LMNATRPM8 | |
| SCHEMBL7890220 | 0.87 | CDC7 (0.52) | XDHCDC7DBF4LMNATRPM8 | |
| SCHEMBL3705153 | 0.84 | XDH (0.61) | XDHCDC7DBF4LMNAABCC4 | |
| SCHEMBL3711471 | 0.79 | XDH (0.54) | XDHCDC7DBF4LMNAABCC4 | |
| SCHEMBL3713964 | 0.79 | XDH (0.65) | XDHCDC7DBF4LMNATRPM8 | |
| SCHEMBL3704800 | 0.76 | XDH (0.79) | XDHLMNAABCC4ABCB11PGR | |
| SCHEMBL13178517 | 0.76 | CDC7 (0.81) | CDC7DBF4LMNATRPM8TP53 | |
| SCHEMBL7886674 | 0.75 | XDH (0.50) | XDHCDC7DBF4LMNATARBP2 | |
| SCHEMBL3712062 | 0.75 | XDH (0.50) | XDHCDC7DBF4LMNATARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |