Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 11/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 11/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7890220 | 0.89 | CDC7 (0.52) | CDC7DBF4LMNATRPM8TP53 | |
| SCHEMBL3712062 | 0.88 | XDH (0.50) | CDC7DBF4LMNASMN1; SMN2KDM4E | |
| SCHEMBL3704472 | 0.87 | XDH (0.55) | CDC7DBF4LMNATRPM8TP53 | |
| SCHEMBL3714429 | 0.83 | LMNA (0.48) | CDC7DBF4LMNATRPM8KDM4E | |
| SCHEMBL3712656 | 0.78 | CDC7 (0.50) | CDC7DBF4LMNATRPM8SMN1; SMN2 | |
| SCHEMBL13178517 | 0.78 | CDC7 (0.81) | CDC7DBF4LMNATRPM8SMN1; SMN2 | |
| SCHEMBL3706676 | 0.78 | CDC7 (0.48) | CDC7DBF4LMNATRPM8SMN1; SMN2 | |
| SCHEMBL7886674 | 0.77 | XDH (0.50) | CDC7DBF4LMNASMN1; SMN2KDM4E | |
| SCHEMBL3712683 | 0.77 | CDC7 (0.48) | CDC7DBF4LMNATRPM8SMN1; SMN2 | |
| SCHEMBL1984283 | 0.76 | CDC7 (0.64) | CDC7DBF4LMNATRPM8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |