Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3708311 | 0.87 | MAPT (0.56) | HTR1AMAPTCYP1A2ADRA1DADRA1A | |
| SCHEMBL3711300 | 0.85 | MAPT (0.70) | MAPTADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3705133 | 0.84 | MAPT (0.58) | HTR1AMAPTADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3706215 | 0.84 | MAPT (0.68) | MAPTADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3709653 | 0.80 | ADRA1D (0.55) | SIGMAR1MAPTADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3710653 | 0.80 | MAPT (0.53) | HTR1AMAPTADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3703905 | 0.79 | MEN1 (0.61) | MAPTADRA1DADRA1AADRA1B | |
| SCHEMBL3709570 | 0.78 | SMN1; SMN2 (0.59) | HTR7MAPT | |
| Hydrochloric Acid SCHEMBL3706389 | 0.77 | SMN1; SMN2 (0.57) | HTR7MAPT | |
| SCHEMBL3704825 | 0.75 | MBTD1 (0.45) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |