Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.46 |
| ▸ | ICMT | O60725 | 5/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708168 | 0.91 | CDC7 (0.44) | CDC7DBF4ICMTTRPM8ALDH1A1 | |
| SCHEMBL3708169 | 0.91 | CDC7 (0.44) | CDC7DBF4ICMTTRPM8ALDH1A1 | |
| SCHEMBL3708167 | 0.91 | CDC7 (0.44) | CDC7DBF4ICMTTRPM8ALDH1A1 | |
| SCHEMBL3707266 | 0.85 | XDH (0.57) | CDC7DBF4ICMTXDH | |
| SCHEMBL3714294 | 0.84 | CDC7 (0.45) | CDC7DBF4ICMTTRPM8ALDH1A1 | |
| SCHEMBL3715575 | 0.82 | CDC7 (0.52) | CDC7DBF4TRPM8ALDH1A1KDM4E | |
| SCHEMBL3706584 | 0.82 | XDH (0.55) | CDC7DBF4XDH | |
| SCHEMBL3707161 | 0.82 | CDC7 (0.49) | CDC7DBF4TRPM8ALDH1A1KDM4E | |
| SCHEMBL7894491 | 0.76 | CDC7 (0.51) | CDC7DBF4TRPM8ALDH1A1KDM4E | |
| SCHEMBL7891786 | 0.75 | CDC7 (0.50) | CDC7DBF4TRPM8ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |