Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 5/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708168 | 1.00 | CDC7 (0.44) | CDC7DBF4ICMTXDHTRPM8 | |
| SCHEMBL3708169 | 1.00 | CDC7 (0.44) | CDC7DBF4ICMTXDHTRPM8 | |
| SCHEMBL3704887 | 0.91 | CDC7 (0.46) | CDC7DBF4ICMTXDHTRPM8 | |
| SCHEMBL3707266 | 0.83 | XDH (0.57) | CDC7DBF4ICMTXDH | |
| SCHEMBL3715827 | 0.83 | CDC7 (0.47) | CDC7DBF4XDHTRPM8KDM4E | |
| SCHEMBL3715828 | 0.83 | CDC7 (0.47) | CDC7DBF4XDHTRPM8KDM4E | |
| SCHEMBL3715829 | 0.83 | CDC7 (0.47) | CDC7DBF4XDHTRPM8KDM4E | |
| SCHEMBL3714294 | 0.82 | CDC7 (0.45) | CDC7DBF4ICMTXDHTRPM8 | |
| SCHEMBL3715575 | 0.80 | CDC7 (0.52) | CDC7DBF4TRPM8KDM4EALDH1A1 | |
| SCHEMBL3706584 | 0.80 | XDH (0.55) | CDC7DBF4XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |