Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | QPCT | Q16769 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542942 | 0.85 | ALDH1A1 (0.86) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL14433882 | 0.85 | ALDH1A1 (0.86) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL3707448 | 0.83 | QPCT (0.62) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL6819847 | 0.82 | MAPT (0.71) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL31706880 | 0.80 | MEN1 (0.67) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL5450386 | 0.79 | MAOB (0.89) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL20536913 | 0.79 | MAOB (1.00) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL15758638 | 0.78 | SMN1; SMN2 (0.66) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL6819840 | 0.78 | MAPT (0.68) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL3822991 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086613-A1 | COMPOUNDS USEFUL AS INHIBITORS AS AMPK | BETAGENON AB (SE) | 2010-08-05 | — | — | WO | disclosed |