Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705022 | 0.83 | ALDH1A1 (0.80) | QPCTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15758317 | 0.81 | KMT2A (0.54) | ALDH1A1MEN1KMT2AMAPTHTR2A | |
| SCHEMBL20496920 | 0.78 | APLNR (0.61) | QPCTALDH1A1SMN1; SMN2TDP1LMNA | |
| SCHEMBL26324037 | 0.75 | APLNR (0.65) | QPCTALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL13735975 | 0.74 | LMNA (0.69) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2226834 | 0.74 | APLNR (0.63) | QPCTALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL14434612 | 0.74 | MAPT (0.78) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14433869 | 0.73 | MEN1 (0.69) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL23175312 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29987898 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086613-A1 | COMPOUNDS USEFUL AS INHIBITORS AS AMPK | BETAGENON AB (SE) | 2010-08-05 | — | — | WO | disclosed |