Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 8/20 | 0.35 |
| ▸ | EDNRA | P25101 | 8/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369625 | 0.80 | EDNRB (0.34) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL10144369 | 0.67 | CYP1A2 (0.42) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL364200 | 0.67 | SMN1; SMN2 (0.34) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL364699 | 0.60 | GAA (0.36) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| Toluene SCHEMBL10523657 | 0.56 | LMNA (0.58) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL4546868 | 0.56 | ADORA2A (0.53) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL15984806 | 0.56 | CYP3A4 (0.42) | POLBLMNAHTTMAPT | |
| SCHEMBL18597143 | 0.56 | CCR1 (0.58) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL13377842 | 0.56 | GRM5 (0.57) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL10727605 | 0.55 | KCNN4 (0.42) | KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |