Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.65 |
| ▸ | ATM | Q13315 | 3/20 | 0.65 |
| ▸ | TACR1 | P25103 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | COMT | P21964 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669175 | 0.83 | ALDH1A1 (0.74) | KMT2AALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL6769005 | 0.81 | ALDH1A1 (0.72) | KMT2AALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL17861570 | 0.81 | TACR1 (0.47) | KMT2AALDH1A1KDM4EATMTACR1 | |
| SCHEMBL19423658 | 0.80 | MAOA (0.46) | KMT2AALDH1A1KDM4EATMTACR1 | |
| Hydrochloric Acid SCHEMBL7405455 | 0.80 | ALDH1A1 (0.70) | KMT2AALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL14318329 | 0.79 | ALDH1A1 (0.88) | KMT2AALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL16236098 | 0.79 | ALDH1A1 (0.71) | KMT2AALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL1779555 | 0.79 | KDM4E (0.67) | KMT2AALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL2096685 | 0.79 | ALDH1A1 (0.67) | KMT2AALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL15859936 | 0.79 | KDM4E (0.67) | KMT2AALDH1A1KDM4EATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |