Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 10/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708922 | 0.81 | SLC6A9 (0.51) | SLC6A9SLC6A5 | |
| SCHEMBL4184530 | 0.81 | SLC6A9 (0.51) | SLC6A9SLC6A5 | |
| SCHEMBL4186582 | 0.81 | SLC6A9 (0.51) | SLC6A9SLC6A5 | |
| SCHEMBL3806592 | 0.76 | SLC6A9 (0.54) | SLC6A9SLC6A5 | |
| SCHEMBL16320729 | 0.68 | AOC3 (0.46) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL30771325 | 0.67 | DRD2 (0.43) | SLC6A2SLC6A3OPRM1OPRD1OPRK1 | |
| SCHEMBL14894964 | 0.66 | AOC3 (0.44) | SLC6A4SLC6A2 | |
| SCHEMBL10781087 | 0.66 | AOC3 (0.54) | — | |
| SCHEMBL10781776 | 0.66 | AOC3 (0.54) | — | |
| Hydrochloric Acid SCHEMBL3710025 | 0.66 | SLC6A9 (0.53) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |