Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 9/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | BLVRB | P30043 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712164 | 0.92 | XDH (0.58) | XDHKDM1AABCC4ABCB11PGR | |
| SCHEMBL3716043 | 0.91 | XDH (0.47) | XDHKDM1AABCC4ABCB11PGR | |
| SCHEMBL7892914 | 0.88 | XDH (0.42) | XDHKDM1AABCC4ABCB11PGR | |
| SCHEMBL3712304 | 0.86 | XDH (0.65) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3709646 | 0.85 | XDH (0.63) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3707418 | 0.85 | XDH (0.63) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3710572 | 0.83 | XDH (0.48) | XDHKDM1AABCC4ABCB11PGR | |
| SCHEMBL3710925 | 0.83 | BTK (0.46) | XDHKDM1A | |
| SCHEMBL3708281 | 0.82 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL7888257 | 0.80 | XDH (0.45) | XDHKDM1AABCC4ABCB11PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | claimed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |