Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716043 | 0.92 | XDH (0.47) | BTKXDHHPGDKDM4EALDH1A1 | |
| SCHEMBL3710572 | 0.91 | XDH (0.48) | XDHKDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL7888123 | 0.89 | SRC (0.42) | BTKHPGDKDM4EALDH1A1CDC7 | |
| SCHEMBL3712069 | 0.86 | XDH (0.54) | XDHKDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL3709450 | 0.85 | XDH (0.52) | XDHKDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL3706016 | 0.85 | XDH (0.52) | XDHKDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL3706958 | 0.83 | XDH (0.55) | XDHKDM1A | |
| SCHEMBL3707452 | 0.83 | XDH (0.50) | XDHKDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL3712164 | 0.81 | XDH (0.58) | XDHKDM1A | |
| SCHEMBL7891799 | 0.81 | CDC7 (0.41) | XDHHPGDKDM4EALDH1A1CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |