Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707088 | 1.00 | GAA (0.61) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11105668 | 0.87 | KMT2A (0.60) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11107857 | 0.87 | GAA (0.63) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11122096 | 0.87 | KMT2A (0.60) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11107861 | 0.87 | GAA (0.63) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11104524 | 0.86 | GAA (0.58) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11104519 | 0.86 | GAA (0.58) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11104514 | 0.86 | GAA (0.58) | GAAPOLBMMP1MMP2MMP9 | |
| SCHEMBL11363464 | 0.82 | TBXA2R (0.65) | GAAPOLBLMNA | |
| SCHEMBL11363915 | 0.82 | TBXA2R (0.65) | GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809584-B2 | N-substituted-N-phenylethylsulfonamides for the identification of biological and pharmacological activity | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S.A. (ES) | 2014-08-19 | — | — | US | disclosed |
| US-20120149909-A1 | N-SUBSTITUTED-N-PHENYLETHYLSULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | AMIRA THERAPEUTICS, S.L. (ES) | 2012-06-14 | — | — | US | disclosed |
| US-20120122710-A1 | LIBRARIES OF N-SUBSTITUTED-N-PHENYLETHYLSULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S. A. (ES) | 2012-05-17 | — | — | US | disclosed |
| US-20120122920-A1 | LIBRARIES OF N-SUBSTITUTED-N-PHENYLETHYLSULFONAMIDES FOR DRUG DISCOVERY | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S. A. (ES) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122920-A1 | LIBRARIES OF N-SUBSTITUTED-N-PHENYLETHYLSULFONAMIDES FOR DRUG DISCOVERY | TST, PNMT, PTPRS | GAA 1983/4885POLB 4211/4885MMP1 4869/4885 |
| US-20120149909-A1 | N-SUBSTITUTED-N-PHENYLETHYLSULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | NAT1, TST, PNMT | GAA 488/4885POLB 4107/4885MMP1 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.