SCHEMBL3707645

SCHEMBL3707645

CCC=CCC=CCC=CCC=CCC=CCCCCOC(CC)C(=O)OC(CO)CO

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.55
CNR2 P34972 3/20 0.55
ALDH1A1 P00352 3/20 0.55
FAAH O00519 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23520505 1.00 CNR1 (0.55) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL3707641 1.00 CNR1 (0.55) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL20086312 0.93 CNR1 (0.50) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL2783735 0.89 ALDH1A1 (0.44) CNR1CNR2ALDH1A1MAPTHPGD
SCHEMBL2783732 0.89 ALDH1A1 (0.44) CNR1CNR2ALDH1A1MAPTHPGD
SCHEMBL20086304 0.87 ALDH1A1 (0.46) CNR1CNR2ALDH1A1MAPTHPGD
SCHEMBL21052408 0.86 ALDH1A1 (0.46) CNR1CNR2ALDH1A1MAPTHPGD
SCHEMBL21052409 0.86 ALDH1A1 (0.46) CNR1CNR2ALDH1A1MAPTHPGD
SCHEMBL21052411 0.85 ALDH1A1 (0.49) CNR1CNR2ALDH1A1MAPTHPGD
SCHEMBL21052413 0.85 ALDH1A1 (0.49) CNR1CNR2ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735436-B2 Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas PRONOVA BIOPHARMA NORGE AS (NO) 2014-05-27 US claimed
US-20140221439-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS PRONOVA BIOPHARMA NORGE AS (NO) 2014-08-07 US disclosed
US-8735436-B2 Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas PRONOVA BIOPHARMA NORGE AS (NO) 2014-05-27 US disclosed
US-20120122940-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS PRONOVA BIOPHARMA NORGE AS (NO) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122940-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS FFAR2, FFAR3, FFAR1 CNR1 119/4885CNR2 35/4885ALDH1A1 695/4885
US-20140221439-A1 POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS FFAR2, FFAR3, FFAR1 CNR1 103/4885CNR2 33/4885ALDH1A1 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.