Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882738 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL3707311 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL101570 | 0.77 | ALDH1A1 (0.69) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL7886437 | 0.76 | MAPT (0.53) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL20377763 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL1625327 | 0.76 | CYP1A2 (0.44) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL14683926 | 0.76 | CYP1A2 (0.44) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL30242608 | 0.76 | CYP1A2 (0.44) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL30515102 | 0.76 | CYP1A2 (0.44) | ALDH1A1MAPK1MAPTPOLBTDP1 | |
| SCHEMBL29445495 | 0.75 | ALDH1A1 (0.71) | ALDH1A1MAPK1MAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094645-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010094644-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010094645-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010094644-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-08-26 | — | — | WO | disclosed |