Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | USP7 | Q93009 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706362 | 0.90 | USP7 (0.67) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL29619258 | 0.90 | USP7 (0.67) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL3712252 | 0.87 | TP53 (0.65) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL3705477 | 0.85 | ALOX15 (0.61) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL3705340 | 0.83 | MEN1 (0.78) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL16904825 | 0.82 | ALOX15 (0.63) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL6781400 | 0.81 | MEN1 (0.72) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL3706307 | 0.81 | USP7 (0.69) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL3714413 | 0.80 | USP7 (0.73) | ALOX15POLBUSP7MEN1KMT2A | |
| SCHEMBL15563413 | 0.80 | ALOX15 (0.60) | ALOX15POLBUSP7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081783-A1 | NOVEL SPECIFIC INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2010-07-22 | — | — | WO | claimed |