Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290192 | 0.92 | RXFP1 (0.36) | RXFP1BRAFNR1H4LRRK2KMT2A | |
| SCHEMBL289051 | 0.90 | RXFP1 (0.39) | RXFP1BRAFNR1H4LRRK2KMT2A | |
| SCHEMBL3704888 | 0.88 | PDE5A (0.38) | RXFP1NR1H4LRRK2KMT2AMEN1 | |
| SCHEMBL31560030 | 0.88 | RXFP1 (0.38) | RXFP1BRAFNR1H4LRRK2KMT2A | |
| SCHEMBL3708470 | 0.86 | RXFP1 (0.34) | RXFP1BRAFNR1H4LRRK2KMT2A | |
| SCHEMBL3703139 | 0.85 | KMT2A (0.39) | RXFP1NR1H4LRRK2KMT2AMEN1 | |
| SCHEMBL3766659 | 0.85 | RXFP1 (0.37) | RXFP1BRAFNR1H4LRRK2KMT2A | |
| SCHEMBL29362690 | 0.85 | RXFP1 (0.37) | RXFP1BRAFNR1H4LRRK2KMT2A | |
| SCHEMBL29360734 | 0.85 | KMT2A (0.39) | RXFP1NR1H4LRRK2KMT2AMEN1 | |
| SCHEMBL3224628 | 0.84 | S1PR3 (0.40) | POLBKDM4ES1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106242998-B | Use of 4-cyano-3-benzoylamino-N-phenyl-benzamides in pesticides | 先正达参股股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| EP-2427427-B1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | NISCH, AADAC, ACHE | RXFP1 4237/4885BRAF 2923/4885NR1H4 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.