Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3705762 | 0.99 | OPRM1 (0.43) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL3703302 | 0.85 | OPRM1 (0.41) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL3707110 | 0.84 | OPRM1 (0.41) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL3806873 | 0.83 | OPRM1 (0.53) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL3717001 | 0.82 | OPRM1 (0.48) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL3707961 | 0.82 | OPRM1 (0.52) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL3706763 | 0.81 | OPRM1 (0.47) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL13283844 | 0.78 | CHRM2 (0.51) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL3709196 | 0.78 | OPRM1 (0.51) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL3713043 | 0.77 | CHRM2 (0.47) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |