Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3707110 | 0.99 | OPRM1 (0.41) | OPRM1HSD11B1MBTD1L3MBTL3WDR5 | |
| SCHEMBL3707934 | 0.85 | OPRM1 (0.43) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL3705762 | 0.84 | OPRM1 (0.43) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL3806873 | 0.80 | OPRM1 (0.53) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL3717001 | 0.80 | OPRM1 (0.48) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL3707961 | 0.79 | OPRM1 (0.52) | OPRM1MBTD1L3MBTL3OGACHRM2 | |
| Hydrochloric Acid SCHEMBL3706763 | 0.78 | OPRM1 (0.47) | OPRM1MBTD1L3MBTL3CHRM2CHRM1 | |
| SCHEMBL17660594 | 0.76 | KDM2B (0.43) | — | |
| SCHEMBL3703305 | 0.76 | MAPT (0.49) | MBTD1L3MBTL3 | |
| Hydrochloric Acid SCHEMBL3712977 | 0.75 | MAPT (0.48) | MBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |