Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468824 | 0.94 | ALDH1A1 (0.35) | KMT2ALMNAHTTALDH1A1KDM4E | |
| SCHEMBL28510935 | 0.85 | ALDH1A1 (0.39) | KMT2ATP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL555799 | 0.84 | KMT2A (0.42) | KMT2ALMNAHTTTP53ALDH1A1 | |
| Water SCHEMBL2725823 | 0.82 | KMT2A (0.41) | KMT2ALMNAHTTTP53ALDH1A1 | |
| SCHEMBL20504316 | 0.81 | ALDH1A1 (0.40) | KMT2ALMNAHTTTP53ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL7567318 | 0.81 | KMT2A (0.41) | KMT2ALMNAHTTALDH1A1CHRM2 | |
| Alcohol SCHEMBL7566185 | 0.81 | ALDH1A1 (0.41) | KMT2ALMNAHTTALDH1A1CHRM2 | |
| SCHEMBL626439 | 0.81 | ALDH1A1 (0.41) | KMT2ALMNAHTTALDH1A1CHRM2 | |
| SCHEMBL2417 | 0.79 | ALDH1A1 (0.45) | KMT2ALMNAHTTALDH1A1CHRM2 | |
| SCHEMBL2229127 | 0.79 | ALDH1A1 (0.45) | KMT2ALMNAHTTALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812464-A2 | INSECTIDICAL POLYPEPTIDES AND METHODS OF USE THEREOF | University of Connecticut (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006052806-A2 | INSECTIDICAL POLYPEPTIDES AND METHODS OF USE THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2006-05-18 | — | — | WO | disclosed |