Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL7566185 | 0.96 | ALDH1A1 (0.41) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL2417 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL9790 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL2229127 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| 2-Mercaptoethanol SCHEMBL1809193 | 0.93 | PTGS1 (0.39) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL20504316 | 0.92 | ALDH1A1 (0.40) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL21752977 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL21752841 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| Sulfuric Acid SCHEMBL6545396 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL21752843 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046158-A1 | RHODACYANINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR TREATING LEISHMANIASIS | HOSHI UNIVERSITY (JP) | 2011-04-21 | — | — | WO | disclosed |
| WO-2011002642-A1 | SENSOR FILMS, METHODS FOR MAKING AND METHODS FOR MONITORING WATER-SOLUBLE POLYMER CONCENTRATIONS | GENERAL ELECTRIC COMPANY (US) | 2011-01-06 | — | — | WO | disclosed |