Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 20/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704782 | 0.90 | ELANE (0.42) | P2RY1 | |
| SCHEMBL3702550 | 0.86 | PTGER3 (0.47) | — | |
| SCHEMBL3702005 | 0.85 | PTGER3 (0.44) | — | |
| SCHEMBL3710717 | 0.84 | PTGER3 (0.41) | — | |
| SCHEMBL3712537 | 0.84 | MEN1 (0.46) | — | |
| SCHEMBL3704487 | 0.82 | TRPV1 (0.42) | P2RY1 | |
| SCHEMBL3703952 | 0.81 | NTRK1 (0.53) | P2RY1P2RY14P2RY2 | |
| SCHEMBL4569777 | 0.81 | AKT1 (0.38) | P2RY1 | |
| SCHEMBL3701028 | 0.81 | FPR2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL3705741 | 0.81 | NTRK1 (0.53) | P2RY1P2RY14P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648086-B2 | 5,6-bicyclic heteroaryl-containing urea compounds as kinase inhibitors | ASCEPION PHARMACEUTICALS, INC. (CN) | 2014-02-11 | — | — | US | disclosed |
| US-20120122895-A1 | 5,6-BICYCLIC HETEROARYL-CONTAINING UREA COMPOUNDS AS KINASE INHIBITORS | JIANG, SHAN | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122895-A1 | 5,6-BICYCLIC HETEROARYL-CONTAINING UREA COMPOUNDS AS KINASE INHIBITORS | FLT3, CSF1R, EPHA2 | P2RY1 441/4885P2RY14 987/4885P2RY2 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.