Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710229 | 0.84 | ADORA2B (0.39) | ADORA2BMAPTGPBAR1ALDH1A1ALOX12 | |
| SCHEMBL833090 | 0.83 | ADORA2B (0.44) | ADORA2BGPBAR1ALDH1A1 | |
| SCHEMBL3707345 | 0.76 | ADORA2B (0.34) | ADORA2BALDH1A1 | |
| SCHEMBL831210 | 0.70 | ADORA2B (0.49) | ADORA2BMAPTALDH1A1 | |
| SCHEMBL9188539 | 0.66 | ADORA2B (0.46) | ADORA2BMAPTALDH1A1 | |
| SCHEMBL831629 | 0.63 | ADORA2B (0.44) | ADORA2BMAPTALDH1A1 | |
| SCHEMBL886958 | 0.63 | GLA (0.47) | HIF1AALDH1A1 | |
| SCHEMBL9319605 | 0.62 | RECQL (0.41) | ADORA2BMAPTGPBAR1ALDH1A1 | |
| SCHEMBL3412296 | 0.62 | KDM4E (0.46) | ADORA2BMAPTALDH1A1 | |
| SCHEMBL830786 | 0.62 | FFAR3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197846-A1 | SUBSTITUTED 6-PHEYLNICOTINIC ACIDS AND THE USE THEREOF | Bayer Animal Health GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009033561-A1 | SUBSTITUTED 6-PHEYLNICOTINIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-03-19 | — | — | WO | disclosed |