1,4-Butanediol

1,4-Butanediol

SCHEMBL37084

CC(C)(Br)C(=O)O.CC(C)(Br)C(=O)O.OCCCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.42
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
PPARA Q07869 2/20 0.40
CAMK2A Q9UQM7 1/20 0.39
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP4F2 P78329 2/20 0.38
CYP4A11 Q02928 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
ARG2 P78540 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TET2 Q6N021 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3726741 0.88 TSHR (0.42) PPARACAMK2ATSHRALDH1A1CYP2D6
Ethylene Glycol SCHEMBL36867 0.88 TSHR (0.42) PPARACAMK2ATSHRALDH1A1CYP2D6
SCHEMBL1236141 0.84 CYP4F2 (0.39) GPR84FFAR1FFAR4PPARACAMK2A
Ethylene Glycol SCHEMBL21581914 0.83 TET2 (0.39) PPARATSHRALDH1A1CYP2D6CYP2C19
Pivalate SCHEMBL6905029 0.82 GPR84 (0.46) GPR84FFAR1FFAR4PPARACAMK2A
SCHEMBL29165520 0.82 CYP4F2 (0.42) GPR84FFAR1FFAR4PPARACAMK2A
SCHEMBL138469 0.82
SCHEMBL28434676 0.80 CYP4F2 (0.46) GPR84FFAR1FFAR4PPARACAMK2A
Pivalate SCHEMBL29150541 0.80 FFAR1 (0.50) GPR84FFAR1FFAR4PPARACAMK2A
Propane SCHEMBL28762288 0.79 TSHR (0.44) TSHRALDH1A1CYP2D6CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8106129-B2 Method for the production of (meth) acrylate-based ABA triblock copolymers EVONIK RÖHM GMBH (DE) 2012-01-31 US claimed
US-8034879-B2 Method for preparation of penta-block copolymers with oh-functionalized blocks based on (meth)acrylate EVONIK ROEHM GMBH (DE) 2011-10-11 US claimed
US-20110086984-A1 METHOD FOR PRODUCING SILYL-FUNCTIONALIZED ABA TRIBLOCK COPOLYMERS ON THE BASIS OF (METH)ACRYLATE EVONIK ROEHM GMBH (DE) 2011-04-14 US claimed
US-20110034623-A1 METHOD FOR PREPARATION OF PENTA-BLOCK COPOLYMERS WITH OH-FUNCTIONALIZED BLOCKS BASED ON (METH)ACRYLATE EVONIK ROEHM GMBH (DE) 2011-02-10 US claimed
US-7868098-B2 Process for preparing (meth) acrylate-based ABA triblock copolymers EVONIK ROEHM GMBH (DE) 2011-01-11 US claimed
US-20100280182-A1 METHOD FOR THE PRODUCTION OF (METH) ACRYLATE-BASED ABA TRIBLOCK COPOLYMERS EVONIK ROEHM GMBH (DE) 2010-11-04 US claimed
EP-2181131-B1 METHOD FOR PREPARATION OF PENTA-BLOCK COPOLYMERS WITH OH-FUNCTIONALIZED BLOCKS BASED ON (METH)ACRYLATE EVONIK ROEHM GMBH (DE) 2010-10-27 EP claimed
EP-2046849-B1 METHOD FOR THE PRODUCTION OF (METH)ACRYLATE-BASED ABA TRIBLOCK COPOLYMERS EVONIK ROEHM GMBH (DE) 2010-06-02 EP claimed
EP-1926762-B1 PROCESS FOR PREPARING (METH)ACRYLATE-BASED ABA TRIBLOCK COPOLYMERS EVONIK ROEHM GMBH (DE) 2009-10-07 EP claimed
US-20080262176-A1 Process for Preparing (Meth) Acrylate-Based Aba Triblock Copolymers EVONIK ROEHM GMBH (DE) 2008-10-23 US claimed
WO-2023248850-A1 VINYL-BASED POLYMER, MANUFACTURING METHOD THEREFOR, AND CURABLE RESIN COMPOSITION 東亞合成株式会社 2023-12-28 WO disclosed
US-8895669-B2 Method for producing ABA-triblock copolymers with a bimodal B-block EVONIK ROEHM GMBH (DE) 2014-11-25 US disclosed
US-8829117-B2 Method for producing ABA-triblock copolymers with a widely distributed B-block EVONIK ROEHM GMBH (DE) 2014-09-09 US disclosed
US-20140206823-A1 METHOD FOR REDUCING THE HALOGEN CONTENT OF A POLYMER EVONIK OIL ADDITIVES GMBH (DE) 2014-07-24 US disclosed
EP-2285849-B1 SILYL-FUNCTIONALIZED ABA TRIBLOCK COPOLYMERS ON THE BASIS OF (METH)ACRYLATE AND PROCESS FOR THEIR PRODUCTION HENKEL AG & CO KGAA (DE) 2014-06-18 EP disclosed
US-20090312498-A1 PROCESS FOR PREPARING HYDROXY-TELECHELIC ATRP PRODUCTS EVONIK ROEHM GMBH (DE) 2009-12-17 US disclosed
US-20090275707-A1 PROCESS FOR PREPARING HALOGEN-FREE ATRP PRODUCTS EVONIK ROEHM GMBH (DE) 2009-11-05 US disclosed
EP-1926762-B1 PROCESS FOR PREPARING (METH)ACRYLATE-BASED ABA TRIBLOCK COPOLYMERS EVONIK ROEHM GMBH (DE) 2009-10-07 EP disclosed
US-20090062508-A1 COPPER REMOVAL FROM ATRP PRODUCTS BY MEANS OF ADDITION OF SULFUR COMPOUNDS EVONIK ROEHM GMBH (DE) 2009-03-05 US disclosed
US-20080262176-A1 Process for Preparing (Meth) Acrylate-Based Aba Triblock Copolymers EVONIK ROEHM GMBH (DE) 2008-10-23 US disclosed