Ethylene Glycol

Ethylene Glycol

SCHEMBL3726741

CC(C)(Br)C(=O)O.OCCO

nearest known ligand 0.42

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP2D6 P10635 1/20 0.39
TET2 Q6N021 1/20 0.37
PPARA Q07869 3/20 0.36
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
KMT2A Q03164 1/20 0.34
PPARG P37231 1/20 0.34
BLM P54132 1/20 0.31
GGT1 P19440 1/20 0.31
CAMK2A Q9UQM7 1/20 0.30
FFAR3 O14843 1/20 0.30
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL36867 1.00 TSHR (0.42) TSHRALDH1A1CYP2C19HIF1ACYP2D6
Ethylene Glycol SCHEMBL21581914 0.94 TET2 (0.39) TSHRALDH1A1CYP2C19HIF1ACYP2D6
1,4-Butanediol SCHEMBL37084 0.88 GPR84 (0.42) TSHRALDH1A1CYP2C19HIF1ACYP2D6
SCHEMBL138469 0.87
Methacrylic Acid SCHEMBL5485831 0.85 TET2 (0.43) TSHRALDH1A1CYP2C19HIF1ACYP2D6
Propane SCHEMBL28762288 0.84 TSHR (0.44) TSHRALDH1A1CYP2C19HIF1ACYP2D6
Hydrochloric Acid SCHEMBL10470923 0.83
Ethane SCHEMBL4575320 0.83
Bromide SCHEMBL258976 0.83
SCHEMBL9898154 0.82 TSHR (0.38) TSHRALDH1A1CYP2C19HIF1ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116462805-A Preparation method and application of water-resistant impact-resistant waterborne polyurethane 山西利根定信息科技有限公司 2023-07-21 CN disclosed
EP-1637550-B1 Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby UNIV CARNEGIE MELLON (US) 2017-09-20 EP disclosed
US-7825199-B1 mediated by transition metal complex in redox reaction of atom transfer Atom Transfer Coupling Reaction to/from initiator or dormant polymer and growing active polymer chain ends; transition metal held in close conjunction with a solid support; salt containing a soluble organic counterion; styrene graft CARNEGIE MELLON UNIVERSITY (US) 2010-11-02 US disclosed
EP-1637550-A2 Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby CARNEGIE-MELLON UNIVERSITY (US) 2006-03-22 EP disclosed
EP-1171496-B1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY UNIV CARNEGIE MELLON (US) 2005-12-07 EP disclosed
US-20040171779-A1 Redox systems; using transition metal complex catalysts; atom transfer radical polymerization CARNEGIE MELLON UNIVERSITY (A NON-PROFIT PENNSYLVANIA ORGANIZATION) 2004-09-02 US disclosed
EP-1171496-A1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY CARNEGIE-MELLON UNIVERSITY (US) 2002-01-16 EP disclosed
WO-2000056795-A1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY CARNEGIE MELLON UNIVERSITY (US) 2000-09-28 WO disclosed