SCHEMBL3708435

SCHEMBL3708435

CN1C2CCC1(C(NC(=O)O)c1ccccc1)CC2

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 19/20 0.76
SLC6A5 Q9Y345 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2605328 0.86 SLC6A9 (1.00) SLC6A9SLC6A5
SCHEMBL2605224 0.86 SLC6A9 (0.79) SLC6A9SLC6A5
SCHEMBL2124242 0.86 SLC6A9 (1.00) SLC6A9SLC6A5
SCHEMBL2605327 0.86 SLC6A9 (1.00) SLC6A9SLC6A5
SCHEMBL2605333 0.84 SLC6A9 (0.62) SLC6A9SLC6A5
SCHEMBL2605325 0.84 SLC6A9 (0.62) SLC6A9SLC6A5
SCHEMBL2605332 0.84 SLC6A9 (0.62) SLC6A9SLC6A5
SCHEMBL2605281 0.84 SLC6A9 (0.74) SLC6A9SLC6A5
SCHEMBL2605245 0.83 SLC6A9 (0.80) SLC6A9SLC6A5
SCHEMBL2605206 0.83 SLC6A9 (0.70) SLC6A9SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2391628-A1 2-AZA-BICYCLOÝ2.2.1¨HEPTANE COMPOUNDS AND USES THEREOF AstraZeneca AB (SE) 2011-12-07 EP disclosed
WO-2010087762-A1 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF ASTRAZENECA AB (SE) 2010-08-05 WO disclosed