Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 15/20 | 0.62 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605325 | 1.00 | SLC6A9 (0.62) | SLC6A9SLC6A5CTSSCTSK | |
| SCHEMBL2605333 | 1.00 | SLC6A9 (0.62) | SLC6A9SLC6A5CTSSCTSK | |
| SCHEMBL7899345 | 0.84 | SLC6A9 (0.64) | SLC6A9SLC6A5 | |
| SCHEMBL7894745 | 0.84 | SLC6A9 (0.64) | SLC6A9SLC6A5 | |
| SCHEMBL7896421 | 0.84 | SLC6A9 (0.64) | SLC6A9SLC6A5 | |
| SCHEMBL3708435 | 0.84 | SLC6A9 (0.76) | SLC6A9SLC6A5 | |
| SCHEMBL2605318 | 0.82 | SLC6A9 (0.60) | SLC6A9 | |
| SCHEMBL2605324 | 0.79 | CA1 (0.39) | SLC6A9CTSSCTSK | |
| SCHEMBL2605328 | 0.77 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL2605327 | 0.77 | SLC6A9 (1.00) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094995-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2012-04-19 | — | — | US | disclosed |
| US-20120094995-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2012-04-19 | — | — | US | disclosed |
| WO-2010087762-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094995-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | SLC1A2, B4GALT1, SLC6A1 | SLC6A9 50/4885SLC6A5 33/4885CTSS 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.