Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.43 |
| ▸ | RORC | P51449 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715369 | 0.86 | THRB (0.55) | THRBRORCMEN1KMT2ALMNA | |
| SCHEMBL3224353 | 0.78 | THRB (0.41) | THRBRORCMEN1KMT2ALMNA | |
| SCHEMBL3708448 | 0.78 | THRB (0.45) | THRBRORCMEN1KMT2ALMNA | |
| SCHEMBL3701809 | 0.77 | THRB (0.40) | THRBRORCMEN1KMT2ALMNA | |
| SCHEMBL3221169 | 0.76 | THRB (0.39) | THRBRORCMEN1KMT2ALMNA | |
| SCHEMBL3226704 | 0.73 | THRB (0.43) | THRBMEN1KMT2ATHRA | |
| SCHEMBL3814388 | 0.73 | ALDH1A1 (0.39) | THRBRORCMEN1KMT2AMAPT | |
| SCHEMBL16496798 | 0.72 | CYP1A2 (0.46) | THRBRORCMEN1KMT2AMAPT | |
| SCHEMBL18932876 | 0.72 | THRB (0.45) | THRBRORCMEN1KMT2AALDH1A1 | |
| SCHEMBL18932867 | 0.72 | MAPT (0.46) | THRBRORCMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |