Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 10/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891474 | 0.89 | CDC7 (0.47) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL3707925 | 0.88 | CDC7 (0.48) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL3708460 | 0.87 | CDC7 (0.49) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL7890658 | 0.82 | LMNA (0.66) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL7884141 | 0.80 | CDC7 (0.45) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL7888953 | 0.78 | ALDH1A1 (0.56) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL7892124 | 0.77 | CDC7 (0.55) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL3712724 | 0.76 | CDC7 (0.55) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL2283795 | 0.75 | CDC7 (0.57) | LMNACDC7DBF4ALDH1A1KDM4E | |
| SCHEMBL3704792 | 0.74 | CDC7 (0.46) | LMNACDC7DBF4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |