Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923385 | 0.87 | SIGMAR1 (0.79) | ALDH1A1SIGMAR1KMT2AMAPTLMNA | |
| SCHEMBL3712719 | 0.87 | MAPT (0.74) | ALDH1A1KMT2AMAPTL3MBTL1RECQL | |
| Hydrochloric Acid SCHEMBL3706847 | 0.85 | MAPT (0.72) | ALDH1A1KMT2AMAPTL3MBTL1RECQL | |
| Hydrochloric Acid SCHEMBL11213408 | 0.85 | SIGMAR1 (0.77) | ALDH1A1SIGMAR1KMT2AMEN1MAPT | |
| SCHEMBL2876304 | 0.83 | SIGMAR1 (0.72) | ALDH1A1SIGMAR1KMT2AMAPTLMNA | |
| SCHEMBL3711524 | 0.81 | DRD4 (0.70) | ALDH1A1SIGMAR1MAPTL3MBTL1RECQL | |
| SCHEMBL3711938 | 0.81 | MAPT (0.61) | ALDH1A1KDM4EKMT2AMAPTL3MBTL1 | |
| SCHEMBL9243053 | 0.80 | TRPV6 (0.64) | ALDH1A1SIGMAR1KDM4E | |
| SCHEMBL3563737 | 0.80 | KDM4E (0.64) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| Hydrochloric Acid SCHEMBL3793856 | 0.80 | DRD4 (0.68) | ALDH1A1SIGMAR1MAPTL3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |