Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 16/20 | 0.49 |
| ▸ | THRA | P10827 | 15/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706436 | 0.85 | THRA (0.65) | THRBTHRA | |
| SCHEMBL3709651 | 0.84 | THRB (0.52) | THRBTHRA | |
| SCHEMBL3707265 | 0.84 | THRA (0.53) | THRBTHRA | |
| SCHEMBL3704031 | 0.79 | THRB (0.38) | THRBTHRA | |
| SCHEMBL3707431 | 0.77 | THRA (0.59) | THRBTHRA | |
| SCHEMBL2170241 | 0.76 | THRA (0.47) | THRBTHRA | |
| SCHEMBL2170237 | 0.76 | THRA (0.47) | THRBTHRA | |
| SCHEMBL3708122 | 0.76 | THRB (0.45) | THRBTHRA | |
| SCHEMBL3705094 | 0.74 | THRB (0.49) | THRBTHRASLC7A5 | |
| SCHEMBL2169569 | 0.72 | THRA (0.46) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |