Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3703903 | 0.99 | CYP2D6 (0.51) | CYP2D6CHRM2CHRM1OPRM1OPRK1 | |
| SCHEMBL3709196 | 0.95 | OPRM1 (0.51) | CYP2D6CHRM2CHRM1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL3808136 | 0.94 | OPRM1 (0.50) | CYP2D6CHRM2CHRM1OPRM1OPRK1 | |
| SCHEMBL13283844 | 0.87 | CHRM2 (0.51) | CYP2D6CHRM2CHRM1OPRM1OPRK1 | |
| SCHEMBL3703344 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1OPRM1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL3708307 | 0.84 | CHRM2 (0.50) | CHRM2CHRM1OPRM1OPRK1OPRL1 | |
| SCHEMBL3714873 | 0.83 | CHRM2 (0.54) | CHRM2CHRM1OPRM1SLC18A3CHRM4 | |
| Hydrochloric Acid SCHEMBL3708326 | 0.82 | CHRM2 (0.53) | CHRM2CHRM1OPRM1SLC18A3CCR5 | |
| Hydrochloric Acid SCHEMBL3705110 | 0.81 | SLC18A3 (0.41) | CHRM2CHRM1OPRM1OPRK1OPRL1 | |
| SCHEMBL3708960 | 0.81 | OPRM1 (0.43) | CYP2D6CHRM2CHRM1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |