Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3705516 | 0.99 | OPRM1 (0.42) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| SCHEMBL3709196 | 0.86 | OPRM1 (0.51) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| Hydrochloric Acid SCHEMBL3808136 | 0.84 | OPRM1 (0.50) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| SCHEMBL3713534 | 0.82 | CYP2D6 (0.47) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| Hydrochloric Acid SCHEMBL3708906 | 0.81 | CYP2D6 (0.46) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| SCHEMBL3708933 | 0.81 | CYP2D6 (0.53) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| Hydrochloric Acid SCHEMBL3703903 | 0.80 | CYP2D6 (0.51) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| SCHEMBL13283844 | 0.79 | CHRM2 (0.51) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| SCHEMBL3713043 | 0.78 | CHRM2 (0.47) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 | |
| SCHEMBL3715359 | 0.78 | L3MBTL3 (0.55) | OPRM1OPRK1OPRL1L3MBTL3MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |