Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 10/20 | 0.35 |
| ▸ | CNR1 | P21554 | 9/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3687763 | 0.99 | ERN1 (0.34) | ERN1CNR2CNR1PKMRXFP1 | |
| SCHEMBL1583247 | 0.83 | ERN1 (0.40) | ERN1PKMRXFP1 | |
| SCHEMBL3709595 | 0.83 | HDAC4 (0.35) | ERN1PKMRXFP1TYRO3MERTK | |
| SCHEMBL1583278 | 0.82 | ERN1 (0.40) | ERN1PKMRXFP1 | |
| SCHEMBL3693692 | 0.82 | ERN1 (0.40) | ERN1PKMRXFP1 | |
| Hydrochloric Acid SCHEMBL3687760 | 0.82 | HDAC4 (0.34) | ERN1PKMRXFP1TYRO3MERTK | |
| SCHEMBL3794236 | 0.82 | ITGB2 (0.36) | ERN1TYRO3MERTK | |
| SCHEMBL3793277 | 0.82 | NOTUM (0.41) | ERN1PKMRXFP1TYRO3MERTK | |
| SCHEMBL3784084 | 0.81 | GPR119 (0.36) | ERN1TYRO3MERTK | |
| SCHEMBL3699956 | 0.81 | SMN1; SMN2 (0.39) | ERN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120121540-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities For Treating Viral Infections | GLAXOSMITHKLINE LLC | 2012-05-17 | — | — | US | disclosed |
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | GLAXOSMITHKLINE LLC | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121540-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities For Treating Viral Infections | OAT, HAVCR2, CPS1 | ERN1 237/4885CNR2 635/4885CNR1 524/4885 |
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | OAT, HAVCR2, CPS1 | ERN1 237/4885CNR2 635/4885CNR1 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.